(4.8) ★★★★★ 

Finally, a migraine supplement made for busy moms.

Tired of migraine stealing time with your family? We’ve got your back with our world's first migraine superblend.
  • Less frequent attacks

  • Gain lasting energy

  • Kiss brain fog goodbye

Free shipping • 30-day risk-free guarantee

Tired of hearing "just drink water"? Us too.

Migraine is more than a headache, so we set out to create an all-in-one, holistic solution for every aspect of your health. 
  • Migraine-free days, in weeks

    13 active studied ingredients means unequalled nutrition - just for people with migraine.
  • Everything you need, in 1 serving per day

    Say goodbye to swallowing capsules and wondering what magnesium to take: we've done the research for you.
  • Yummy, sugar-free mango flavor

    Real mango plus nature-derived sweeteners make for a delicious taste you'll love making a habit.

Formulated to fight migraine (all of it).

Migraine free days
Made with science's best ingredients to give you fewer migraine attacks.
Long lasting energy
Vitamins and minerals to power you through your day and never miss a beat.
Fighting brain fog
Created to give you a clear head and sharp thinking when you need it most.
Peaceful, better sleep
We hate worrying about nighttime attacks: you deserve a good night's rest (finally).



Servings per day
1 scoop
13 pills
Created by experts for migraine
Research-backed forms and doses
Money-back guarantee
Made in US-based, CGMP facility
Pill after pill, day after day
One scoop a day keeps migraine away.
We got tired of taking handfuls of pills every day. We worked with tastemasters over months of R&D to make The Brain Superblend yummy, delightful, and simple:
  • Stir 1 scoop into 12 ounces of water.

  • Enjoy daily. Works in yogurt & smoothies!

(4.8) ★★★★★
The Brain Superblend
Control your migraine in 1-12 weeks
Meet the world’s most comprehensive migraine support formula: combining proven, science-backed ingredients in a delicious 1x/day serving.
  • Reduces migraine frequency

  • Combats brain fog & low energy

  • Tasty, mango flavor 1 serving/day

Purchase options



Migraine moms have spoken.
"I used to miss out on time with my kids because of migraines. Melina gave me my life back!"



“I was skeptical, but Melina delivered. No more migraines stealing precious time from my family."



“Melina is a total game-changer for my migraines. I can actually be a mom again without pain!”



Meet our powerful ingredients.
We put every single ingredient recommended by the American Headache Society in one scoop.
30-Day Risk-Free Promise

Supports Neural Health*

Relaxes blood vessels and supports healthy cognition.*
Helps with production of energy and protects brain cells.*
Crucial to cellular energy and mitochondrial activity.*

Protects Cellular Function*

Protects cells from damage and improves mitochondrial function, which may lessen migraine symptoms.*
400mcg DFE
Plays an integral role in producing neurotransmitters that regulate mood and perception of pain.*
Protects the brain against damage from oxidative stress that contributes to migraines.*
2500 IU
Enhances nerve cell function, reduces inflammation in the brain, and regulates key hormones associated with migraines.*

Enhances Mood & Focus*

Helps in the production of neurotransmitters that regulate pain perception.*
Essential for energy production in the brain which can stabilize cellular function.*
Boosts mood-regulating neurotransmitters and reduces nerve inflammation.*
Reduces inflammation*
Inhibits the release of inflammatory substances that provoke migraines and constrict blood vessels.*
Helps regulate magnesium and vitamin D, both crucial for migraine management.*
This highly absorbable form of zinc regulates glutamate, a neurotransmitter linked to migraines.*
30-Day Risk-Free Promise

Frequently asked questions

How does it work?

The Brain Superblend is designed to be your daily ritual to help you manage migraine better. One scoop a day in 12-16 oz is all you need, preferably in the morning.

The ingredients in The Brain Superblend have all been shown in clinical trials and studies to reduce migraine attacks, reduce pain, as well as lessen other symptoms like brain fog and anxiety.

Most people experienced in those trials experienced a reduction of 50% of in the number of migraine attacks they got, along with less pain and other improvements (more energy, less anxiety, to name a few). 

Everyone is different, but we've leaned on the science as much as we could to create something that'll likely help improve your quality of life!

What's your money-back guarantee?

We've wasted plenty of hard-earned money on treatments that worked for others, but not us. If this happens to you, we won't leave you hanging.

Studies have shown that the ingredients take around 3 months to reach maximum benefits - but if you don't experience any benefits in your first month and aren't 100% satisfied, contact us within 30 days of your first order to initiate the process of receiving a refund for your original order.

What's special about The Brain Superblend?

With 13 active researched-backed ingredients, the Brain Superblend is the most comprehensive migraine supplement available in a single serving.

We also got really tired of pills, so we made it a delicious powder instead.
How did you create the formula?
Our co-founder, Jeremy, has long struggled with his own neurological challenges in the form of cluster headache. Cluster headache may have "headache" in the name, but - like migraine - is so much more than "just a headache". Over the course of his medical history, he's experimented and familiarized himself with just about every potentially beneficial supplement out there to create his own support superblend.

After meeting dozens of others who expressed interest in the superblend as well, we refined the formula by partnering with nutritionists, doctors, and neurologists to ensure our blend was as effective - and safe - as possible.

We weren't done, of course; we then worked with a leading US-based R&D lab to further refine the formula, make it taste great, and source quality ingredients. The process took over a year, but we think it was worth it - and hope you agree.
Do you offer free samples?
We wish we could. The main reason we don't: it takes time to see benefits. Many see differences in a month, but studies have shown it taking up to 3 months for some that all depends on their individual needs. A short sample wouldn't tell you much about whether or not we can help.

Instead, we offer a money-back guarantee: if you don't see any benefits within your first month, we'd be happy to refund you.

Is it safe?

Safety is our top priority. The FDA has guidelines on how to manufacture supplements, called Current Good Manufacturing Processes, or cGMP. Melina blends in the United States, in facilities that follow cGMP regulations and are regularly inspected by the FDA. We only use ingredients that are classified by the FDA as Generally Recognized As Safe (GRAS) in doses that are highly effective, but well under studied upper tolerable limits.

We're also deadly serious about testing: we test 3 times for heavy metals (at higher California Prop 65 standards) and potency to ensure you're receiving something safe and at the advertised potency.

How long does it take to see results?

When taken daily, it's likely you'll see results in your first month. This is based on supporting published ingredient studies, which generally run for 3-4 months. They've shown that benefits generally emerge during or after the first month. Everyone's different, so results may come sooner (or later). Keep at it.

You may notice words like "likely" and "generally" - it'd be irresponsible to promise the moon (we've been burned before). There's a lot we don't know about migraine, so it's impossible to guarantee results for everyone. Studies have shown benefits for many, but if you're part of the minority - we've got our 30 Day Promise to get you your money back if you're not satisfied. 

Can I take it on an empty stomach?

Sure thing! You can take our superblend on an empty stomach, and many find this works best for them to maximize absorption of the nutrients. However, everyone's body is unique, so if you find that it doesn't sit well on an empty stomach, feel free to take it with a meal or split the dose into a half dose, twice daily. 

Who is this product not for?

First, make sure you talk to your doctor about this superblend, especially if you’re taking prescription medication! All our ingredients are drug-free, but vitamins, minerals and herbs can still interact with some drugs and make them less effective. Notably, folks taking blood thinning medication should check with their doctors before taking CoQ-10 and Feverfew, both present in our formula. This list is not complete. 

Our formula was not designed for children. Pregnant and nursing people should also consult with their doctors, as the effects of our ingredients has not been studied on these folks.

I usually don't like stevia, can I still enjoy The Brain Superblend?

Absolutely! We use just a dash of pure stevia extract to gently sweeten the natural flavors to turn every scoop into a delightful ritual for you. 

That means each serving contains very small amounts of stevia. We're talking less than 1% per scoop! 

So, if you're worried about the taste, we'd still encourage you to give it a try: we worked on the flavor for 10+ months to make sure it didn't have that bitter stevia aftertaste! And if you don't like it after all, you can get a refund on your first order thanks to our 30-Day Protection Promise. 

Note that if you know stevia triggers your migraine, you might want to wait until we release a stevia-free option, which we're actively working on. 
We’ve dealt with cluster headaches for over 20 years and know what it’s like to feel powerless to an invisible illness. 
We’ve also wasted time and money on treatments that didn’t work, so our 30-Day Protection Promise refunds you if you’re not satisfied. We won't let you down.
Creating The Brain Superblend with doctors and nutritionists, we’re out to provide a comprehensive tool to help you regain control on your terms. We can't wait to see what you’ll accomplish with more migraine-free days.
Jeremy & Laïla, Co-Founders

Never miss out on time with your kids again.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, or cure any disease. The information on this site is for educational purposes only and is not medical advice. Please refer to our Terms of Use and speak with a healthcare professional to ensure Melina is for you. Melina is for adults 18 and over.